Hoechst 34580 (tetrahydrochloride)
Hoechst 34580 tetrahydrochloride is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore, Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
Product Specifications
CAS Number
2310135-08-9
Product Name Alternative
HOE 34580 tetrahydrochloride
UNSPSC
12171500
Target
Amyloid-β
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Purity
99.47
Solubility
H2O : 2.67 mg/mL (ultrasonic)
Smiles
CN1CCN(C2=CC=C3C(N=C(C4=CC=C5C(N=C(C6=CC=C(N(C)C)C=C6)N5)=C4)N3)=C2)CC1.[H]Cl.[H]Cl.[H]Cl.[H]Cl
Molecular Formula
C27H33Cl4N7
Molecular Weight
597.41
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Citation 01
Available Sizes
Frequently Asked Questions
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