E-4031 (Standard)
E-4031 (Standard) is the analytical standard of E-4031. This product is intended for research and analytical applications. E-4031 is a selective hERG potassium channel blocker for use in class III anti-arrhythmic studies[1].
Product Specifications
CAS Number
113559-13-0
UNSPSC
12352100
Hazard Statement
H302
Target
Potassium Channel; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Cardiovascular Disease
Purity
98.78
Smiles
CS(=O)(NC1=CC=C(C(C2CCN(CCC3=NC(C)=CC=C3)CC2)=O)C=C1)=O.[H]Cl.[H]Cl
Molecular Formula
C21H29Cl2N3O3S
Molecular Weight
474.44
Precautions
H302
References & Citations
[1]Daisuke Izumi, et al. Effects of bepridil versus E-4031 on transmural ventricular repolarization and inducibility of ventricular tachyarrhythmias in the dog. Pacing Clin Electrophysiol. 2010 Aug;33 (8) :950-9.|[2] E E Verheijck, et al. Effects of delayed rectifier current blockade by E-4031 on impulse generation in single sinoatrial nodal myocytes of the rabbit. Circ Res. 1995 Apr;76 (4) :607-15.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed and dry storage, away from light and moisture
Scientific Category
Reference Standards
Available Sizes
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