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E-4031 (Standard)

E-4031 (Standard) is the analytical standard of E-4031. This product is intended for research and analytical applications. E-4031 is a selective hERG potassium channel blocker for use in class III anti-arrhythmic studies[1].

Product Specifications

CAS Number

113559-13-0

UNSPSC

12352100

Hazard Statement

H302

Target

Potassium Channel; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Cardiovascular Disease

Purity

98.78

Smiles

CS(=O)(NC1=CC=C(C(C2CCN(CCC3=NC(C)=CC=C3)CC2)=O)C=C1)=O.[H]Cl.[H]Cl

Molecular Formula

C21H29Cl2N3O3S

Molecular Weight

474.44

Precautions

H302

References & Citations

[1]Daisuke Izumi, et al. Effects of bepridil versus E-4031 on transmural ventricular repolarization and inducibility of ventricular tachyarrhythmias in the dog. Pacing Clin Electrophysiol. 2010 Aug;33 (8) :950-9.|[2] E E Verheijck, et al. Effects of delayed rectifier current blockade by E-4031 on impulse generation in single sinoatrial nodal myocytes of the rabbit. Circ Res. 1995 Apr;76 (4) :607-15.

Shipping Conditions

Blue Ice

Storage Conditions

4°C, sealed and dry storage, away from light and moisture

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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