Kb NB 142-70 (Standard)
Kb NB 142-70 (Standard) is the analytical standard of kb NB 142-70. This product is intended for research and analytical applications. kb NB 142-70 is a potent PKD inhibitor, with IC50s of 28.3, 58.7 and 53.2 nM for PKD1, PKD2, and PKD3, respectively. kb NB 142-70 also has antitumor activity.
Product Specifications
CAS Number
1233533-04-4
UNSPSC
12352100
Target
PKD; Reference Standards
Related Pathways
Apoptosis; Others
Field of Research
Cancer
Smiles
O=C1NCCSC2=C1SC3=CC=C(O)C=C32
Molecular Formula
C11H9NO2S2
Molecular Weight
251.32
References & Citations
[1]Lavalle CR, et al. Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility. BMC Chem Biol. 2010 May 5;10:5.|[2]James Sinnett-Smith, et al. Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling. Am J Physiol Cell Physiol. 2014 May 15; 306 (10) : C961-C971.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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