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K-832

K-832 is an orally active IL-1β secretion inhibitor. K-832 can be used in the research of rheumatoid arthritis[1][2].

Product Specifications

CAS Number

225666-85-3

UNSPSC

12352005

Target

Interleukin Related

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

O=C1C=C(C2=CC=C(Cl)C=C2)C(C3=CC=C(SC)C=C3)=NN1CC4=CC=CC=C4

Molecular Formula

C24H19ClN2OS

Molecular Weight

418.94

References & Citations

[1]Dumont F J. The interleukin-1 families of cytokines and receptors: therapeutic potential for immunomodulation and the treatment of inflammatory disorders. Expert Opinion on Therapeutic Patents, 2006, 16 (7) : 879-912.|[2]Halim S A, et al. Attempt to explore the binding mechanism of IL-1β inhibitors via molecular docking studies. Med. Chem, 2015, 5 (10) : 452-457.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

IL-1

Frequently Asked Questions

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