3,5-O-[1,1,3,3-Tetrakis (1-methylethyl) -1,3-disiloxanediyl] cytidine
Selected Variant
HY-154633
Size: 1 Each
3,5-O-[1,1,3,3-Tetrakis (1-methylethyl) -1,3-disiloxanediyl] cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H](O[Si](C(C)C)(C(C)C)O[Si](C(C)C)(C(C)C)OC2)[C@@H]2O[C@H]1N3C=CC(N)=NC3=O
Molecular Formula
C21H39N3O6Si2
Molecular Weight
485.72
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Price
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