Temsavir (Standard)

Temsavir (Standard) is the analytical standard of Temsavir. This product is intended for research and analytical applications. Temsavir (BMS-626529) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.

Product Specifications

CAS Number

[701213-36-7]

UNSPSC

12352100

Target

HIV; Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

O=C(N1CCN(C(C2=CC=CC=C2)=O)CC1)C(C3=CNC4=C3C(OC)=CN=C4N5C=NC(C)=N5)=O

Molecular Formula

C24H23N7O4

Molecular Weight

473.48

References & Citations

[1]Nowicka-Sans B, et al. In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068. Antimicrobial Agents and Chemotherapy (2012), 56 (7), 3498-3507.|[2]Nettles RE, et al. Pharmacodynamics, safety, and pharmacokinetics of BMS-663068, an oral HIV-1 attachment inhibitor in HIV-1-infected subjects. J Infect Dis. 2012 Oct 1;206 (7) :1002-11.