Fostemsavir-d8
Fostemsavir-d8 (BMS-663068-d8) is deuterium labeled Fostemsavir. Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
Product Specifications
Product Name Alternative
BMS-663068-d8
UNSPSC
12352005
Target
HIV; Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C(C1=CN(COP(O)(O)=O)C2=C1C(OC)=CN=C2N3N=C(C)N=C3)C(N4C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C4([2H])[2H])C(C5=CC=CC=C5)=O)=O
Molecular Formula
C25H18D8N7O8P
Molecular Weight
591.54
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Nowicka-Sans B, et al. In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068. Antimicrob Agents Chemother. 2012 Jul;56 (7) :3498-507.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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