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L-687414

L-687414 is an orally active glycine-site NMDA receptor antagonist or low-potency partial agonist. L-687414 has anticonvulsant activity[1].

Product Specifications

CAS Number

130931-65-6

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

IGluR

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

N[C@H]1C(N(C[C@H]1C)O)=O

Molecular Formula

C5H10N2O2

Molecular Weight

130.15

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Tricklebank MD, et al. The anticonvulsant and behavioural profile of L-687,414, a partial agonist acting at the glycine modulatory site on the N-methyl-D-aspartate (NMDA) receptor complex. Br J Pharmacol. 1994 Nov;113 (3) :729-36.

Shipping Conditions

Room temperature

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Frequently Asked Questions

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