L-687414
L-687414 is an orally active glycine-site NMDA receptor antagonist or low-potency partial agonist. L-687414 has anticonvulsant activity[1].
Product Specifications
CAS Number
[130931-65-6]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
IGluR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
N[C@H]1C(N(C[C@H]1C)O)=O
Molecular Formula
C5H10N2O2
Molecular Weight
130.15
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Tricklebank MD, et al. The anticonvulsant and behavioural profile of L-687,414, a partial agonist acting at the glycine modulatory site on the N-methyl-D-aspartate (NMDA) receptor complex. Br J Pharmacol. 1994 Nov;113 (3) :729-36.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Curated Selection
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