(E/Z) -NSC-687852
(E/Z) -NSC-687852 is a isomer of NSC-687852 (HY-13989) . NSC687852 (b-AP15) is a specific inhibitor of the deubiquitinating enzymes UCHL5 and Usp14[1].
Product Specifications
CAS Number
[330450-45-8]
Product Name Alternative
(E/Z) -b-AP15
UNSPSC
12352005
Target
Deubiquitinase
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C1/C(CN(C(C=C)=O)C/C1=C\C2=CC=C([N+]([O-])=O)C=C2)=C\C3=CC=C([N+]([O-])=O)C=C3
Molecular Formula
C22H17N3O6
Molecular Weight
419.39
References & Citations
[1]Berndtsson M, et al. Induction of the lysosomal apoptosis pathway by inhibitors of the ubiquitin-proteasome system. Int J Cancer. 2009;124 (6) :1463-1469.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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