Capivasertib (Standard)
Capivasertib (Standard) is the analytical standard of Capivasertib. This product is intended for research and analytical applications. Capivasertib (AZD5363) is an orally active and potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1, Akt2 and Akt3, respectively.
Product Specifications
CAS Number
1143532-39-1
UNSPSC
12352100
Target
Akt; Autophagy; Reference Standards
Related Pathways
Autophagy; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C(C1(N)CCN(C2=C3C(NC=C3)=NC=N2)CC1)N[C@H](C4=CC=C(Cl)C=C4)CCO
Molecular Formula
C21H25ClN6O2
Molecular Weight
428.92
References & Citations
[1]Davies BR, et al. Preclinical pharmacology of AZD5363, an inhibitor of AKT: pharmacodynamics, antitumor activity, and correlation of monotherapy activity with genetic background. Mol Cancer Ther. 2012 Apr;11 (4) :873-87.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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