Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

(Rac) -Rotigotine (hydrochloride) (Standard)

(Rac) -Rotigotine (hydrochloride) (Standard) is the analytical standard of (Rac) -Rotigotine (hydrochloride) . This product is intended for research and analytical applications. (Rac) -Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Kis of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.

Product Specifications

CAS Number

[102120-99-0]

UNSPSC

12352100

Target

5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Endocrinology; Neurological Disease

Smiles

OC1=C2CCC(N(CCC)CCC3=CC=CS3)CC2=CC=C1.[H]Cl

Molecular Formula

C19H26ClNOS

Molecular Weight

351.93

References & Citations

[1]Wood M, et al. Rotigotine is a potent agonist at dopamine D1 receptors as well as at dopamine D2 and D3 receptors. Br J Pharmacol. 2015 Feb;172 (4) :1124-35.|[2]Scheller D, et al. The in vitro receptor profile of rotigotine: a new agent for the treatment of Parkinson's disease. Naunyn Schmiedebergs Arch Pharmacol. 2009 Jan;379 (1) :73-86.|[3] Fenu S, et al. In vivo dopamine agonist properties of rotigotine: Role of D1 and D2 receptors. Eur J Pharmacol. 2016 Oct 5;788:183-91.|[4]Radad K, et al. Neuroprotective effect of rotigotine against complex I inhibitors, MPP+ and rotenone, in primary mesencephalic cell culture. Folia Neuropathol. 2014;52 (2) :179-86.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-15394R/

Scientific Category

Reference Standards

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

PRC1 Polyclonal Antibody
JOT-AP13288-01 50ul

PRC1 Polyclonal Antibody

Ask
View Details
PRC1 Polyclonal Antibody
JOT-AP13288-02 100ul

PRC1 Polyclonal Antibody

Ask
View Details
FNDC1 Polyclonal Antibody
E55A01840 100 µg

FNDC1 Polyclonal Antibody

Ask
View Details
Rat AREG (Amphiregulin) ELISA Kit
ER21645 96 Tests

Rat AREG (Amphiregulin) ELISA Kit

Ask
View Details
Scn10a Mouse Monoclonal Antibody [Clone ID: N134/12]
75-166 100 µL

Scn10a Mouse Monoclonal Antibody [Clone ID: N134/12]

Ask
View Details
GENLISA™ Human Septin-2 (SEPT2) ELISA
KBH6136 96 Well

GENLISA™ Human Septin-2 (SEPT2) ELISA

Ask
View Details