Lucitanib (Standard)
Lucitanib (Standard) is the analytical standard of Lucitanib. This product is intended for research and analytical applications. Lucitanib (E-3810) is a novel dual inhibitor of VEGFR and FGFR, potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 with IC50s of 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively[1][2][3].
Product Specifications
CAS Number
1058137-23-7
UNSPSC
12352100
Target
FGFR; Reference Standards; VEGFR
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(NC)C1=CC=CC2=C1C=CC(OC3=CC=NC4=CC(OCC5(N)CC5)=C(OC)C=C43)=C2
Molecular Formula
C26H25N3O4
Molecular Weight
443.49
References & Citations
[1]Bello E, et al. E-3810 is a potent dual inhibitor of VEGFR and FGFR that exerts antitumor activity in multiple preclinical models. Cancer Res. 2011 Feb 15;71 (4) :1396-405.|[2]Colzani M, et al. Quantitative chemical proteomics identifies novel targets of the anti-cancer multi-kinase inhibitor E-3810. Mol Cell Proteomics. 2014 Jun;13 (6) :1495-509.|[3]Bello E, et al. The tyrosine kinase inhibitor E-3810 combined with NSC 125973 inhibits the growth of advanced-stage triple-negative breast cancer xenografts. Mol Cancer Ther. 2013 Feb;12 (2) :131-40
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV650373 1.0 µg DNA
MYBL2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)
Sign In for Pricing
View Details 
IMSAHUHLAABCW632CPERCPCY55200 200 Tests
Anti Human HLA-A,B,C Flow Cytometry Monoclonal Clone W632 PerCP/Cyanine5.5 Ready To Use 200 Tests
Sign In for Pricing
View Details E28PB2472 100 µL
Deoxyguanosine Kinase (DGUOK) Rabbit Polyclonal Antibody (C-term)
Sign In for Pricing
View Details MBS7191815 Inquire
Rabbit anti-Escherichia coli (strain UTI89/UPEC) SECM Polyclonal Antibody
Sign In for Pricing
View Details 
K1843602 1.0 µg DNA
RNR1 sgRNA CRISPR Lentivector (Human) (Target 1)
Sign In for Pricing
View Details