C791-0064
C791-0064 is a RAD52 inhibitor. C791-0064 specifically binds to RAD52 and disrupts its single-strand annealing activity. C791-0064 specifically inhibits the proliferation of cancer cells with BRCA2 deficiency, inducing DNA damage and apoptosis (apoptosis) . C791-0064 can be used for the study of BRCA mutation-related cancers (such as breast cancer and ovarian cancer) [1].
Product Specifications
CAS Number
[902940-64-1]
UNSPSC
12352005
Target
Apoptosis; DNA/RNA Synthesis
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(C1=CC(NC(C2=CC=CC=C2S3)=O)=C3C=C1)NCCCN(CC4)CCC4N5CCCCC5
Molecular Formula
C27H34N4O2S
Molecular Weight
478.65
References & Citations
[1]Yang Q, et al. Identification of a RAD52 Inhibitor Inducing Synthetic Lethality in BRCA2-Deficient Cancer Cells. Front Pharmacol. 2021 Apr 29;12:637825.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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