MC-Phe-Lys (MMT) -PABOH
MC-Phe-Lys (MMT) -PABOH is a linker. MC-Phe-Lys (MMT) -PABOH can be used to synthesize the immunoconjugate BR96-Phe-Lys-PABC-DOX. MC-Phe-Lys (MMT) -PABOH can be used in the research of colorectal cancer and ovarian cancer[1][2].
Product Specifications
CAS Number
159857-65-5
UNSPSC
12352005
Target
Drug Intermediate
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(C=CC1=O)N1CCCCCC(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(NC3=CC=C(C=C3)CO)=O)CCCCNC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=C(C=C6)OC)=O)=O
Molecular Formula
C52H57N5O7
Molecular Weight
864.04
References & Citations
[1]Dubowchik GM, et al. Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: model studies of enzymatic drug release and antigen-specific in vitro anticancer activity. Bioconjug Chem. 2002 Jul-Aug;13 (4) :855-69. |[2]Yao H, et al. Methods to Design and Synthesize Antibody-Drug Conjugates (ADCs) . Int J Mol Sci. 2016 Feb 2;17 (2) :194.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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