Δ2-Avermectin B1a

Δ²-Avermectin B₁ₐ (Compound 3) is an antiparasitic agent targeting glutamate-gated chloride channels (GluCls) in the neuromuscular system of invertebrates. Δ²-Avermectin B₁ₐ enhances chloride ion influx, leading to hyperpolarization of the neuromuscular cell membrane, inhibition of neural signal transmission, and ultimately paralysis and death of parasites. Δ²-Avermectin B₁ₐ is promising for research of agricultural pests[1].

Product Specifications

CAS Number

110415-68-4

UNSPSC

12352005

Target

Chloride Channel; Parasite

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel

Field of Research

Neurological Disease

Smiles

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