Dynasore (Standard)
Dynasore (Standard) is the analytical standard of Dynasore. This product is intended for research and analytical applications. Dynasore is a cell-permeable dynamin inhibitor with an IC50 of 15 μM. Dynasore blocks cell migration.
Product Specifications
UNSPSC
12352100
Target
Autophagy; Dynamin; HSV; Reference Standards; Virus Protease
Related Pathways
Anti-infection; Autophagy; Cytoskeleton; Others
Field of Research
Metabolic Disease
Smiles
O=C(C1=C(O)C=C2C=CC=CC2=C1)N/N=C/C3=CC=C(O)C(O)=C3
Molecular Formula
C18H14N2O4
Molecular Weight
322.31
References & Citations
[1]Macia E, et al. Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell. 2006 Jun;10 (6) :839-50.|[2]Mues MB, et al. Dynasore disrupts trafficking of herpes simplex virus proteins. J Virol. 2015 Jul;89 (13) :6673-84.|[3]Gao D, et al. Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart. PLoS One. 2013 Apr 15;8 (4) :e60967.|[4]Li G, et al. Dynasore Improves Motor Function Recovery via Inhibition of Neuronal Apoptosis and Astrocytic Proliferation after Spinal Cord Injury in Rats. Mol Neurobiol. 2016 Nov 7.|[5]Liang Ma, et al. Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration. Cell Res. 2015 Jan;25 (1) :24-38.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15304R/
Scientific Category
Reference Standards
CAS Number
[304448-55-3]
Available Sizes
Curated Selection
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