Dynasore (Standard)

Dynasore (Standard) is the analytical standard of Dynasore. This product is intended for research and analytical applications. Dynasore is a cell-permeable dynamin inhibitor with an IC50 of 15 μM. Dynasore blocks cell migration.

Product Specifications

CAS Number

[304448-55-3]

UNSPSC

12352100

Target

Autophagy; Dynamin; HSV; Reference Standards; Virus Protease

Related Pathways

Anti-infection; Autophagy; Cytoskeleton; Others

Field of Research

Metabolic Disease

Smiles

O=C(C1=C(O)C=C2C=CC=CC2=C1)N/N=C/C3=CC=C(O)C(O)=C3

Molecular Formula

C18H14N2O4

Molecular Weight

322.31

References & Citations

[1]Macia E, et al. Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell. 2006 Jun;10 (6) :839-50.|[2]Mues MB, et al. Dynasore disrupts trafficking of herpes simplex virus proteins. J Virol. 2015 Jul;89 (13) :6673-84.|[3]Gao D, et al. Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart. PLoS One. 2013 Apr 15;8 (4) :e60967.|[4]Li G, et al. Dynasore Improves Motor Function Recovery via Inhibition of Neuronal Apoptosis and Astrocytic Proliferation after Spinal Cord Injury in Rats. Mol Neurobiol. 2016 Nov 7.|[5]Liang Ma, et al. Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration. Cell Res. 2015 Jan;25 (1) :24-38.