Anhydroleucovorin (Standard)

Rosiridin (Standard) is the analytical standard of Rosiridin. This product is intended for research and analytical applications. Rosiridin inhibits MAO A and MAO B with potential beneficial effect in depression and senile dementia. Rosiridin shows an inhibition of 83.8% against MAO B at 10 μM (pIC50=5.38) [1].

Product Specifications

CAS Number

[7444-29-3]

UNSPSC

12352005

Target

Drug Intermediate; Reference Standards

Related Pathways

Others

Field of Research

Others; Cancer

Smiles

O=C1C2=C(NC(N)=N1)NC[C@@]3([H])N2C=[N+](C4=CC=C(C=C4)C(N[C@H](C([O-])=O)CCC(O)=O)=O)C3

Molecular Formula

C20H21N7O6

Molecular Weight

455.42

References & Citations

[1]M J OSBORN, et al. Participation of anhydroleucovorin in the hydroxymethyl tetrahydrofolic dehydrogenase system. Biochim Biophys Acta,1957,26, 3.|[2]K Motycka, et al. Localized chemotherapy of Gardner's lymphosarcoma of C3H mice using combinations of carrier-sorbed antifolics and detoxicating tetrahydrofolates. Czech Med,1981,4, 1.