JZL195 (Standard)
JZL195 (Standard) is the analytical standard of JZL195. This product is intended for research and analytical applications. JZL195 is a selective and efficacious dual fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) inhibitor with IC50s of 2 and 4 nM, respectively[1].
Product Specifications
CAS Number
1210004-12-8
UNSPSC
12352100
Target
Autophagy; FAAH; MAGL; Reference Standards
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O=C(OC1=CC=C([N+]([O-])=O)C=C1)N(CC2)CCN2CC3=CC(OC4=CC=CC=C4)=CC=C3
Molecular Formula
C24H23N3O5
Molecular Weight
433.46
References & Citations
[1]Long JZ, et al. Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. Proc Natl Acad Sci U S A. 2009 Dec 1;106 (48) :20270-5.|[2]Anderson WB, et al. Actions of the dual FAAH/MAGL inhibitor JZL195 in a murine inflammatory pain model. Neuropharmacology. 2014 Jun;81:224-30.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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