Vistusertib (Standard)
Vistusertib (Standard) is the analytical standard of Vistusertib. This product is intended for research and analytical applications. Vistusertib (AZD2014) is an ATP competitive mTOR inhibitor with an IC50 of 2.81 nM. AZD2014 inhibits both mTORC1 and mTORC2 complexes.
Product Specifications
CAS Number
1009298-59-2
UNSPSC
12352100
Target
Apoptosis; Autophagy; mTOR; Reference Standards
Related Pathways
Apoptosis; Autophagy; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C(NC)C1=CC=CC(C2=CC=C3C(N=C(N4[C@@H](C)COCC4)N=C3N5[C@@H](C)COCC5)=N2)=C1
Molecular Formula
C25H30N6O3
Molecular Weight
462.54
References & Citations
[1]Guichard SM, et al. AZD2014, an inhibitor of mTORC1 and mTORC2, is highly effective in ER+ breast cancer when administered using intermittent or continuous schedules. Mol Cancer Ther. 2015 Nov;14 (11) :2508-18.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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