Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

GSK2636771 (Standard)

GSK2636771 (Standard) is the analytical standard of GSK2636771. This product is intended for research and analytical applications. GSK2636771 is a potent, selective and orally bioavailable inhibitor of PI3Kβ with a Ki of 0.89 nM and an IC50 of 5.2 nM, showing 900-fold selectivity over p110α and p110γ, and 10-fold selectivity over p110δ isoforms.

Product Specifications

CAS Number

1372540-25-4

UNSPSC

12352100

Target

PI3K; Reference Standards

Related Pathways

Others; PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

CC1=NC2=C(C(O)=O)C=C(C=C2N1CC3=CC=CC(C(F)(F)F)=C3C)N4CCOCC4

Molecular Formula

C22H22F3N3O3

Molecular Weight

433.42

References & Citations

[1]Weigelt B, et al. PI3K pathway dependencies in endometrioid endometrial cancer cell lines. Clin Cancer Res. 2013, 19 (13), 3533-3544.|[2]Hosford SR, et al. Combined inhibition of both p110α and p110β isoforms of phosphatidylinositol 3-kinase is required for sustained therapeutic effect in PTEN-deficient, ER+ breast cancer. Clin Cancer Res. 2016 Nov 30

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

MHC II, Mouse (MK-D6), 0.2mg/mL
BNUB2007-100 1x 100 µL

MHC II, Mouse (MK-D6), 0.2mg/mL

Sign In for Pricing
View Details
Recombinant Human SH2D1A/SAP Protein (His Tag)
PKSH033379-01 10 µg

Recombinant Human SH2D1A/SAP Protein (His Tag)

Sign In for Pricing
View Details
Recombinant Human SH2D1A/SAP Protein (His Tag)
PKSH033379-02 50 µg

Recombinant Human SH2D1A/SAP Protein (His Tag)

Sign In for Pricing
View Details
TagFP, AlpSdAbs® VHH (Biotin)
HA710187 100 µg

TagFP, AlpSdAbs® VHH (Biotin)

Sign In for Pricing
View Details
p16INK4a Mouse Monoclonal Antibody [A4A5]
HA600026 100 µL

p16INK4a Mouse Monoclonal Antibody [A4A5]

Sign In for Pricing
View Details
OVCA1 (DPH1) Human Gene Knockout Kit (CRISPR)
KN221955LP 1 Kit

OVCA1 (DPH1) Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details