BIHC
BIHC is a TNF blocker with anti-inflammatory activity. BIHC can significantly inhibit the proliferation of hepatocellular carcinoma (HCC) cells and exhibits potent cytotoxicity against the HepG2 cell line, capable of inducing cell apoptosis , while demonstrating relatively low toxicity towards normal hepatocytes. Additionally, BIHC can be used for research on inflammatory bowel disease (IBD) [1].
Product Specifications
CAS Number
[1642826-40-1]
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family; IFNAR; Interleukin Related; NF-κB; TNF Receptor
Related Pathways
Apoptosis; Immunology/Inflammation; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Inflammation/Immunology
Purity
98.0
Smiles
O=C1OC2=C(C(O)=C1C(C3=C(O)C4=C(C=CC=C4)OC3=O)C5=C(Cl)N=C(CCCC)N5)C=CC=C2
Molecular Formula
C26H21ClN2O6
Molecular Weight
492.91
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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