(±) -BAY-7081
(±) -BAY-7081 is a racemate of BAY-7081 (HY-152106) . BAY-7081 is a potent, selective, orally active and soluble cyanopyridone-based PDE9A inhibitor with an IC50 of 15 nM[1].
Product Specifications
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Purity
99.06
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N#CC1=C(N(CC2)CCC32CC3)C4=C(NC1=O)C(CCC)CNC4.Cl
Molecular Formula
C19H27ClN4O
Molecular Weight
362.90
References & Citations
[1]Meibom D, et al. BAY-7081: A Potent, Selective, and Orally Bioavailable Cyanopyridone-Based PDE9A Inhibitor. J Med Chem. 2022 Dec 22;65 (24) :16420-16431.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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