Pyridostatin (trihydrochloride)
Pyridostatin (RR82) trihydrochloride is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin trihydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin trihydrochloride targets the proto-oncogene Src. Pyridostatin trihydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells[1][2].
Product Specifications
CAS Number
[2517456-88-9]
Product Name Alternative
RR82 (trihydrochloride)
UNSPSC
12352100
Target
G-quadruplex
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Purity
98.06
Smiles
O=C(C1=CC(OCCN)=CC(C(NC2=NC3=C(C(OCCN)=C2)C=CC=C3)=O)=N1)NC4=CC(OCCN)=C5C=CC=CC5=N4.Cl.Cl.Cl
Molecular Formula
C31H35Cl3N8O5
Molecular Weight
706.02
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15176C/Pyridostatin-trihydrochloride-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
