Trisulfo-Cy3 Methyltetrazine
Trisulfo-Cy3 Methyltetrazine is a click chemistry reagent containing an methyltetrazine group. Methyltetrazine-activated Cy3 probe reacts with TCO-containing compounds via an Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures[1][2].
Product Specifications
CAS Number
1676067-48-3
UNSPSC
12352005
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
O=C(CCCCCN1C2=CC=C(S(=O)(O)=O)C=C2C(C)(C)/C1=C\C=C\C3=[N+](CCCS(=O)(O)=O)C4=C(C3(C)C)C=C(S(=O)([O-])=O)C=C4)NCC5=CC=C(C6=NN=C(C)N=N6)C=C5
Molecular Formula
C42H49N7O10S3
Molecular Weight
908.07
References & Citations
[1]Cy3 Methyltetrazine. |[2]Vera F C Ferreira, et al. In Vivo Pretargeting Based on Cysteine-Selective Antibody Modification with IEDDA Bioorthogonal Handles for Click Chemistry. Bioconjug Chem. 2021 Jan 20;32 (1) :121-132.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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