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SPAA-52 (ammonium)

SPAA-52 (ammonium) is a low molecular weight protein tyrosine phosphatase (LMW-PTP) inhibitor (IC50 = 4 nM; IC50 = 1.2 nM) . SPAA-52 (ammonium) can be used in the research of diabetes mellitus[1].

Product Specifications

UNSPSC

12352211

Target

Phosphatase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

[O-]S(=O)(NC(NC1=CC(Br)=C(C)C(Br)=C1)=O)=O.[NH4+]

Molecular Formula

C8H11Br2N3O4S

Molecular Weight

405.06

References & Citations

[1]He R, et al. Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors. J Med Chem. 2022 Oct 27;65 (20) :13892-13909.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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