Calcitetrol
Calcitetrol (1α, 24, 25-Trihydroxy VD3) is the hormonally active form of vitamin D with three hydroxyl groups. IC50 value: Target: Calcitriol increases blood calcium levels ([Ca2+]) by promoting absorption of dietary calcium from the gastrointestinal tract and increasing renal tubular reabsorption of calcium, thus reducing the loss of calcium in the urine. Calcitriol also stimulates release of calcium from bone by its action on the specific type of bone cells referred to as osteoblasts, causing them to release RANKL, which in turn activates osteoclasts.
Product Specifications
CAS Number
72203-93-1
Product Name Alternative
1α, 24, 25-Trihydroxy VD3
UNSPSC
12352211
Target
VD/VDR
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H](C[C@H](O)C/1=C)CC1=C\C=C2[C@@](CC[C@@H]3[C@@H](CCC(O)C(C)(O)C)C)([H])[C@]3(C)CCC\2
Molecular Formula
C27H44O4
Molecular Weight
432.64
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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