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(E/Z) -Rilzabrutinib

Rilzabrutinib (PRN1008) is an orally active Bruton's tyrosine kinase (BTK) inhibitor with anti-inflammatory and immunomodulatory activities. Rilzabrutinib can be used in the research of various inflammatory and immune-related diseases such as acute respiratory distress syndrome and sepsis[1].

Product Specifications

CAS Number

1575591-66-0

Product Name Alternative

(E/Z) -PRN1008

UNSPSC

12352005

Hazard Statement

H315-H319

Target

Btk

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

NC1=C2C(C3=C(C=C(OC4=CC=CC=C4)C=C3)F)=NN([C@H]5CN(CCC5)C(/C(C#N)=C/C(C)(N6CCN(C7COC7)CC6)C)=O)C2=NC=N1

Molecular Formula

C36H40FN9O3

Molecular Weight

665.76

Precautions

P264-P280-P302+P352-P362+P364

References & Citations

[1]KR TW, et al. JPWO2021216696A5. 2024-05-01

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Launched

Frequently Asked Questions

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