FAK ligand-2
FAK ligand-2 is a FAK inhibitor and a ligand for the target protein of PROTAC (FAK) . FAK ligand-2 can be used to synthesize BSJ-04-146 (HY-179512) [1].
Product Specifications
CAS Number
[2414478-49-0]
UNSPSC
12352005
Target
FAK; Ligands for Target Protein for PROTAC
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
CNC(C1=CC=CC=C1NC2=CC(NC3=CC(C)=C(C=C3OC(C)C)C4CCNCC4)=NC=C2C(F)(F)F)=O
Molecular Formula
C29H34F3N5O2
Molecular Weight
541.61
References & Citations
[1]Koide E, et al. Development and Characterization of Selective FAK Inhibitors and PROTACs with In Vivo Activity. Chembiochem. 2023 Oct 4;24 (19) :e202300141.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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