Irampanel (hydrochloride)
Irampanel hydrochloride (BIIR 561-CL) is an AMPA receptor and voltage-dependent sodium channel blocker. Irampanel hydrochloride inhibits Kainic acid -induced currents in rat cortical neurons[1].
Product Specifications
CAS Number
206260-34-6
Product Name Alternative
BIIR-561-CL
UNSPSC
12352005
Target
IGluR; Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CN(C)CCOC(C=CC=C1)=C1C2=NC(C3=CC=CC=C3)=NO2.Cl
Molecular Formula
C18H20ClN3O2
Molecular Weight
345.82
References & Citations
[1]Weiser T, et al. Characterization of the anticonvulsant and neuroprotectant BIIR 561 CL in vitro: effects on native and recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362 (4-5) :419-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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