Irampanel (hydrochloride)

Irampanel hydrochloride (BIIR 561-CL) is an AMPA receptor and voltage-dependent sodium channel blocker. Irampanel hydrochloride inhibits Kainic acid (HY-N2309) -induced currents in rat cortical neurons[1].

Product Specifications

CAS Number

[206260-34-6]

Product Name Alternative

BIIR-561-CL

UNSPSC

12352005

Target

IGluR; Sodium Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

CN(C)CCOC(C=CC=C1)=C1C2=NC(C3=CC=CC=C3)=NO2.Cl

Molecular Formula

C18H20ClN3O2

Molecular Weight

345.82

References & Citations

[1]Weiser T, et al. Characterization of the anticonvulsant and neuroprotectant BIIR 561 CL in vitro: effects on native and recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362 (4-5) :419-26.