CST530

CST530 is an inhibitor of apoptosis protein (IAP) antagonist. CST530 is an IAP-type Ligands for E3 Ligase. CST530 binds to the BIR3 domain of IAP and interferes with its function, thereby promoting the ubiquitination and degradation of cIAP1. CST530 can be used to prepare PROTACs[1].

Product Specifications

CAS Number

[847137-53-5]

UNSPSC

12352005

Target

IAP; Ligands for E3 Ligase

Related Pathways

Apoptosis; PROTAC

Field of Research

Cancer

Smiles

CN[C@H](C(N[C@@H](C1CCCCC1)C(N2C[C@H](C[C@H]2C(N[C@@H]3CCCC4=CC=CC=C43)=O)OC5=CC=CC=C5)=O)=O)C

Molecular Formula

C33H44N4O4

Molecular Weight

560.73

References & Citations

[1]Ng YLD, et al. Heterobifunctional Ligase Recruiters Enable pan-Degradation of Inhibitor of Apoptosis Proteins. J Med Chem. 2023 Apr 13;66 (7) :4703-4733.