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Guanosine triphosphate-d14 (dilithium)

Guanosine triphosphate-d14 (GTP-d14) dilithium is a deuterium labeled Guanosine triphosphate. Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19[1].

Product Specifications

Product Name Alternative

GTP-d14 (dilithium)

UNSPSC

12352005

Target

DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog; SARS-CoV

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Concentration

100 mM in 182.11 μL Tris HCl/D2O buffer pH=7.5

Purity

96.6

Smiles

O=P(O[2H])(O[Li])OP(OP(OC([2H])([2H])[C@@]1([2H])O[C@](N2C(N=C(N([2H])[2H])N([2H])C3=O)=C3N=C2[2H])([2H])[C@](O[2H])([2H])[C@]1([2H])O[2H])(O[2H])=O)(O[Li])=O

Molecular Formula

C10D14Li2N5O14P3

Molecular Weight

549.13

References & Citations

[1]Abdo A Elfiky, et al. Anti-HCV, nucleotide inhibitors, repurposing against COVID-19. Life Sci. 2020 May 1;248:117477.

Shipping Conditions

Blue Ice

Storage Conditions

Solution, -20°C, 2 years

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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