DNQX (Standard)
DNQX (Standard) is the analytical standard of DNQX. This product is intended for research and analytical applications. DNQX (FG 9041), a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively) [1].
Product Specifications
CAS Number
2379-57-9
UNSPSC
12352100
Target
IGluR; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Cancer
Smiles
O=C1C(NC2=CC([N+]([O-])=O)=C([N+]([O-])=O)C=C2N1)=O
Molecular Formula
C8H4N4O6
Molecular Weight
252.14
References & Citations
[1]Honoré T, et al. Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science. 1988;241 (4866) :701-703.|[2]Lee SH, et al. Selective excitatory actions of DNQX and CNQX in rat thalamic neurons. J Neurophysiol. 2010;103 (4) :1728-1734.|[3]Sharp JW, et al. DNQX inhibits phencyclidine (PCP) and ketamine induction of the hsp70 heat shock gene in the rat cingulate and retrosplenial cortex. Brain Res. 1995;687 (1-2) :114-124.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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