(Rac) -MK 0686
(Rac) -MK 0686 is the racemate of MK 0686. MK 0686 is a bradykinin B1 receptor antagonist[1].
Product Specifications
CAS Number
[1159193-97-1]
UNSPSC
12352005
Target
Bradykinin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Smiles
O=C(C1=C(C2=CC=C(C(C)NC(C3(CC3)NC(C(F)(F)F)=O)=O)C(F)=C2)C=CC=C1Cl)OC
Molecular Formula
C22H19ClF4N2O4
Molecular Weight
486.84
References & Citations
[1]Tang C, et al. CYP2C75-Involved Autoinduction of Metabolism in Rhesus Monkeys of Methyl 3-Chloro-3′-fluoro-4′-{ (1 R) -1-[ ({1-[ (trifluoroacetyl) amino] cyclopropyl} carbonyl) amino] ethyl}-1, 1′-biphenyl-2-carboxylate (MK-0686), a Bradykinin B1 Receptor Antagonist[J]. The Journal of pharmacology and experimental therapeutics, 2008, 325 (3) : 935-946.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bradykinin B1 Receptor (B1R)
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