20:4 Lyso PI
20:4 Lyso PI is a selective G protein-coupled receptor GPR55 agonist. 20:4 Lyso PI triggers cell rounding in GPR55-expressing HEK293 cells, with an EC50 value of 10 nM. 20:4 Lyso PI promotes RhoA activation and subsequent ROCK-dependent cytoskeletal rearrangement. 20:4 Lyso PI activates the ERK signaling pathway and elevates intracellular free calcium. 20:4 Lyso PI can be used for the study of immune diseases[1].
Product Specifications
CAS Number
1246430-04-5
UNSPSC
12352211
Target
Calcium Channel; ERK; GPR55
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; Membrane Transporter/Ion Channel; Neuronal Signaling; Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Smiles
O[C@H]1[C@@H](OP(O)(OC[C@@H](COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)O)=O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
Molecular Formula
C29H49O12P
Molecular Weight
620.67
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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