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ERK1 antibody

Product Specifications

Background

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Synonyms

Mitogen-activated protein kinase 3 (MAP kinase 3, MAPK 3)|ERT2|Extracellular signal-regulated kinase 1 (ERK-1)|Insulin-stimulated MAP2 kinase|MAP kinase isoform p44 (p44-MAPK)|Microtubule-associated protein 2 kinase|p44-ERK1|MAPK3|ERK1|PRKM3

Host

Rabbit

Reactivity

Human

Immunogen

mitogen-activated protein kinase 3

Target

ERK1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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