ERK1 antibody
Product Specifications
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Synonyms
Mitogen-activated protein kinase 3 (MAP kinase 3, MAPK 3) |ERT2|Extracellular signal-regulated kinase 1 (ERK-1) |Insulin-stimulated MAP2 kinase|MAP kinase isoform p44 (p44-MAPK) |Microtubule-associated protein 2 kinase|p44-ERK1|MAPK3|ERK1|PRKM3
Gene ID
5595
UniProt
P27361
Host
Rabbit
Reactivity
Human
Immunogen
Mitogen-activated protein kinase 3
Target
ERK1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Immunology, Neuroscience, Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
43 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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