K34c (hydrochloride)
K34c hydrochloride is a potent and selective α5β1 integrin antagonist. By inhibiting α5β1 integrin, K34c hydrochloride reduces chemotherapy-induced premature senescence and promotes apoptosis. K34c hydrochloride can be used in glioblastoma research[1].
Product Specifications
CAS Number
[2986315-25-5]
UNSPSC
12352005
Target
Apoptosis; Integrin
Related Pathways
Apoptosis; Cytoskeleton
Field of Research
Cancer
Purity
98.85
Smiles
O=C(O)[C@H](CC1=CC=C(OCCCNC2=NC=CC=C2)C=C1)NC(C3=C(C)C=CC=C3C)=O.Cl
Molecular Formula
C26H30ClN3O4
Molecular Weight
483.99
References & Citations
[1]Martinkova E, et al. alpha5beta1 integrin antagonists reduce chemotherapy-induced premature senescence and facilitate apoptosis in human glioblastoma cells. Int J Cancer. 2010 Sep 1;127 (5) :1240-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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