Stemregenin 1 (Standard)

Stemregenin 1 (Standard) is the analytical standard of Stemregenin 1. This product is intended for research and analytical applications. Stemregenin 1 is a potent aryl hydrocarbon receptor (AhR) antagonist with IC50 of 127 nM.

Product Specifications

CAS Number

[1227633-49-9]

UNSPSC

12352100

Target

Aryl Hydrocarbon Receptor; Reference Standards

Related Pathways

Immunology/Inflammation; Others

Field of Research

Cancer

Smiles

CC(C)N1C2=NC(C3=CSC4=C3C=CC=C4)=NC(NCCC5=CC=C(O)C=C5)=C2N=C1

Molecular Formula

C24H23N5OS

Molecular Weight

429.54

References & Citations

[1]Boitano AE, et al. Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells.  Science. 2010 Sep 10;329 (5997) :1345-8.|[2]Gao H, et al. Suppression of homeobox transcription factor VentX promotes expansion of human hematopoietic stem/multipotent progenitor cells. J Biol Chem. 2012 Aug 24;287 (35) :29979-87.