VU0506013
VU0506013 is a selective positive allosteric modulator of Y4R (KB = 34.9 nM) . VU0506013 can be used in the development of anti-obesity agents targeting Y4R[1].
Product Specifications
CAS Number
[1207036-87-0]
UNSPSC
12352005
Target
Neuropeptide Y Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Metabolic Disease
Smiles
O=C(N1CCCC1)C(C=C2NC(COC3=C(C)C=CC=C3)=O)=CN(C)C2=O
Molecular Formula
C20H23N3O4
Molecular Weight
369.41
References & Citations
[1]Schüß C, et al. Structure-Activity Relationship Study of the High-Affinity Neuropeptide Y4 Receptor Positive Allosteric Modulator VU0506013. J Med Chem. 2023 Jul 13;66 (13) :8745-8766.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149593/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NPY Y4 receptor
Curated Selection
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