VU0506013

VU0506013 is a selective positive allosteric modulator of Y4R (KB = 34.9 nM) . VU0506013 can be used in the development of anti-obesity agents targeting Y4R[1].

Product Specifications

CAS Number

[1207036-87-0]

UNSPSC

12352005

Target

Neuropeptide Y Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Metabolic Disease

Smiles

O=C(N1CCCC1)C(C=C2NC(COC3=C(C)C=CC=C3)=O)=CN(C)C2=O

Molecular Formula

C20H23N3O4

Molecular Weight

369.41

References & Citations

[1]Schüß C, et al. Structure-Activity Relationship Study of the High-Affinity Neuropeptide Y4 Receptor Positive Allosteric Modulator VU0506013. J Med Chem. 2023 Jul 13;66 (13) :8745-8766.