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Imepitoin (Standard)

Imepitoin (Standard) is the analytical standard of Imepitoin. This product is intended for research and analytical applications. Imepitoin (AWD 131-138) is a new low-affinity partial benzodiazepine receptor agonist with potent anticonvulsant and anxiolytic properties in rodent models.

Product Specifications

CAS Number

188116-07-6

UNSPSC

12352100

Target

GABA Receptor; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

O=C1N=C(N2CCOCC2)CN1C3=CC=C(Cl)C=C3

Molecular Formula

C13H14ClN3O2

Molecular Weight

279.72

References & Citations

[1]Sigel E, et al. The antiepileptic drug AWD 131-138 stimulates different recombinant isoforms of the rat GABA (A) receptor through the benzodiazepine binding site. Neurosci Lett. 1998 Apr 3;245 (2) :85-8.|[2]Yasar S, et al. Evaluation of the novel antiepileptic drug, AWD 131-138, for benzodiazepine-like discriminative stimulus and reinforcing effects in squirrel monkeys. Eur J Pharmacol. 2003 Apr 4;465 (3) :257-65.|[3]Loscher W, et al. Anticonvulsant efficacy of the low-affinity partial benzodiazepine receptor agonist ELB 138 in a dog seizure model and in epileptic dogs with spontaneously recurrent seizures. Epilepsia. 2004 Oct;45 (10) :1228-39.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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