3,7,2',4'-Tetramethoxy-5-hydroxyflavone
BCRP/ABCG2-IN-1 is the inhibitor of breast cancer resistance protein (BCRP/ABCG2), with IC50 of 5.98 μM, that can be used in multidrug resistance of breast cancer[1].
Product Specifications
CAS Number
[19056-75-8]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
BCRP
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
O=C1C(OC)=C(C2=C(OC)C=C(OC)C=C2)OC3=C1C(O)=CC(OC)=C3
Molecular Formula
C19H18O7
Molecular Weight
358.34
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Kapil Juvale, et al. Synthesis and biological evaluation of flavones and benzoflavones as inhibitors of BCRP/ABCG2. Eur J Med Chem. 2013 Sep:67:115-26.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
138281-Biotin 100 µL
RAGE (Receptor for Advanced Glycosylation End Products, Advanced Glycosylation End Product-specific Receptor, AGER) (Biotin)
Ask
View Details 
MBS7227429-01 48 Well
Mouse Coiled-coil domain-containing protein 116 (CCDC116) ELISA Kit
Ask
View Details MBS7227429-02 96 Well
Mouse Coiled-coil domain-containing protein 116 (CCDC116) ELISA Kit
Ask
View Details 
MBS7227429-03 5x 96 Well
Mouse Coiled-coil domain-containing protein 116 (CCDC116) ELISA Kit
Ask
View Details MBS7227429-04 10x 96 Well
Mouse Coiled-coil domain-containing protein 116 (CCDC116) ELISA Kit
Ask
View Details