FXIIa-IN-1 (hydrochloride)

FXIIa-IN-1 hydrochloride is the hydrochloride of FXIIa-IN-1 (HY-149396) . FXIIa-IN-1 (Compound 22) is a Factor XIIa inhibitor (Kiapp: 97.8 nM) . FXIIa-IN-1 can be used for research of thrombosis[1].

Product Specifications

CAS Number

[3052551-20-6]

UNSPSC

12352005

Target

Thrombin

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Smiles

O=C(C1=CC2=CC(OC)=C(OC)C=C2OC1=O)OC3=CC4=C(C(N)=NC=C4)C=C3.[H]Cl

Molecular Formula

C21H17ClN2O6

Molecular Weight

428.82

References & Citations

[1]Davoine C, et al. Coumarins as factor XIIa inhibitors: Potency and selectivity improvements using a fragment-based strategy. Eur J Med Chem. 2023 Nov 5;259:115636.