Dexelvucitabine (Standard)

Dexelvucitabine (Standard) is the analytical standard of Dexelvucitabine. This product is intended for research and analytical applications. Dexelvucitabine (Reverset; d-d4FC), a Cytidine (HY-B0158) analog, is an orally active nucleoside reverse transcriptase inhibitor. Dexelvucitabine is a powerful agent against HIV-1-resistant viruses containing a thymidine analog and/or M184V mutation in the viral polymerase. Dexelvucitabine is a 2′-Deoxycytidine antiretroviral agent[1].

Product Specifications

CAS Number

[134379-77-4]

UNSPSC

12352100

Target

HIV; Reference Standards; Reverse Transcriptase

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

O=C1N(C=C(C(N)=N1)F)[C@]2([H])O[C@@H](C=C2)CO

Molecular Formula

C9H10FN3O3

Molecular Weight

227.19

References & Citations

[1]Brenda I Hernandez-Santiago, et al. Antiviral and cellular metabolism interactions between Dexelvucitabine and lamivudine. Antimicrob Agents Chemother. 2007 Jun;51 (6) :2130-5.|[2]L Ma, et al. Pharmacokinetics of the antiviral agent beta-D-2',3'-didehydro-2',3'-dideoxy-5-fluorocytidine in rhesus monkeys. Antimicrob Agents Chemother. 1999 Feb;43 (2) :381-4.