RF03176
RF03176 is an aquaporin-9 (AQP-9) inhibitor, also exhibiting moderate inhibition effecs on mAQP3 and mAQP7. RF03176 shows no activity against mAQP8[1].
Product Specifications
CAS Number
[685123-50-6]
UNSPSC
12352005
Target
Aquaporin
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Others
Smiles
O=C(NC1=CC2=C(N=NS2)C=C1)NC3=CC=CC=C3
Molecular Formula
C13H10N4OS
Molecular Weight
270.31
References & Citations
[1]Jelen S, et al. Aquaporin-9 protein is the primary route of hepatocyte glycerol uptake for glycerol gluconeogenesis in mice. J Biol Chem. 2011 Dec 30;286 (52) :44319-25.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148823/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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