PTX-BD10-2
PTX-BD10-2 (BD10-2) is an orally active TrkB/C modulator. PTX-BD10-2 ameliorates BFCN degeneration. PTX-BD10-2 restores cholinergic neurite integrity, alleviates cholinergic neurite atrophy. PTX-BD10-2 can be used in the research of Alzheimer's disease[1].
Product Specifications
CAS Number
[1627834-10-9]
Product Name Alternative
BD10-2
UNSPSC
12352005
Target
Trk Receptor
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
COCCN(CCOC)C1=CC=C(C(C)C2=CC=C(N(CCOC)CCOC)C=C2)C=C1
Molecular Formula
C26H40N2O4
Molecular Weight
444.61
References & Citations
[1]Gonzalez S, et al. Small molecule modulation of TrkB and TrkC neurotrophin receptors prevents cholinergic neuron atrophy in an Alzheimer's disease mouse model at an advanced pathological stage. Neurobiol Dis. 2022 Jan;162:105563.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TrkB; TrkC
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