Ganglioside GD3 (d18:1/12:0)

Ganglioside GD3 (d18:1/12:0) is a type of glycosphingolipid, the d18:1 indicates the sphingosine base, and the 12:0 represents the fatty acid part which is lauric acid. Ganglioside GD3 (d18:1/12:0) is a crucial intermediate in the biosynthesis pathway of gangliosides and is mainly found in the brain tissues of mammals. Ganglioside GD3 (d18:1/12:0) plays significant roles in development, cell signal transduction, and various diseases[1][2].

Product Specifications

CAS Number

[138749-26-5]

UNSPSC

12352005

Target

Biochemical Assay Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Smiles

OC([C@@]1(O[C@@]([C@@H]([C@H](C1)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)O[C@@H]2[C@H]([C@@H](O[C@@H]([C@@H]2O)CO)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3O)O)OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCC)=O)CO)O)=O

Molecular Formula

C57H104N2O21

Molecular Weight

1153.44

References & Citations

[1]Li TA, Schnaar RL. Congenital Disorders of Ganglioside Biosynthesis. Prog Mol Biol Transl Sci. 2018;156:63-82. |[2]Merrill Jr AH, Sandhoff K. Sphingolipids: Metabolism and cell signaling. InNew comprehensive biochemistry 2002 Jan 1 (Vol. 36, pp. 373-407) . Elsevier.