BTK-IN-21
BTK-IN-21 (Compound 12) is a BTK inhibitor with an IC50 of 33 nM. BTK-IN-21 can be used for research in cancer and autoimmunity therapies[1].
Product Specifications
CAS Number
[2170788-98-2]
UNSPSC
12352005
Target
Btk
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer; Inflammation/Immunology
Smiles
OC1CCC(CC1)NC2=NC(CC3=CC=CC=C3)=CC(NC4=NC5=C(S4)C=C(CC)C=C5)=N2
Molecular Formula
C26H29N5OS
Molecular Weight
459.61
References & Citations
[1]Bavi R, et al. Exploration of Novel Inhibitors for Bruton's Tyrosine Kinase by 3D QSAR Modeling and Molecular Dynamics Simulation. PLoS One. 2016 Jan 19;11 (1) :e0147190.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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